1.Hosting and treatment of biological samples in the biobank centralized CSISP.
It has the capability of handling and Storage of a large number of samples in the biobank's centralized CSISP.
The coordinator of this platform is Jacobo Santamaría Martínez, Director of CSISP Biobank.

The services offered are:
- Custody of typical samples.
- Cell cultures.
- Immortalization of lymphocytes.
- Separation of blood components.
- Gomoginizacion tissue / cells.
- Automated extraction of nucleic acids.
- Removing proteins.
 
Platform Infrastructure:
  CSISP biobank:
- Board of extractions. This room is equipped to perform blood draws for those donors who move to CSISP. It is necessary consumables for blood collection and a computer with access to SGI.
- Reception and Processing Laboratory. In this laboratory processed biological samples reach the laboratory. In this laboratory also places the horizontal laminar flow hood to prepare the PCR reagent mix.
- Molecular Biology Laboratory prepared for the amplification of DNA testing integrity and traceability of samples with a thermal cycler, fountains and buckets of electrophoresis, microwave, thermoblocks, temperature-controlled baths.
- Laboratory Quality Control and Final Processing, is the closet to paraffin blocks and the second of the filing of the FTA cards, Nanodrop ND2000, Micronic plate sealer.
- Laboratory of Cell Cultures of type II is equipped with CO2 incubator, inverted microscope, inert gas pressure reducer, tanning Bio-II incubators.
- Board of Storage and Cryopreservation has ultrafreezers at -80 ° C and CO2 bullets that will supply gas to freezers, nitrogen tank at -196 °C.
 

3. Genetic studies, decentralized laboratories of genetics and molecular biology of integrated hospitals in the RVB.

Decentralized platform in several laboratories in Genetics and Molecular Biology of integrated hospitals in the RVB, and which constitute the reference laboratories for the determinations of PCGCCV.
Both physicians and technical staff of this platform has the experience and capacity to ensure the services offered by it. All laboratories involved in quality assurance program EMQN genetic analysis.  

Services:
- Cytogenetics.
- FISH.
- Genotyping.
- SSCP.
- Heteroduplex.
- Analysis of point mutations.
- Analysis of fragments.
- MLPA (Analysis of large rearrangements, methylation ,..).
- Expression via qRT-PCR gene.
- Sequencing.
 
Platform Infrastructure:
H. Faith University
H. General de Elche.
Molecular Biology Laboratory. Valencian Institute of Oncology Foundation:
- Auto Exhaust System Migration nucleic acids PSS 12GC.
- Tissue Homogenizer Fast-Prep-24 (MP-Diagnostics).
- 1 Beecher Tissue arrayer. - 1 ELISA plate reader MultiRead 400 (Athos).
- 5 cyclers from Applied Biosystems (2700, 9700, 9800fast, 2 verities)
- 1 team of Real-Time PCR (7500 fast from Applied Biosystems)
- 1 16-capillary 3130xl sequencer AB
- 1 fluorescence microscope (Axioimager Z1)

4. Studies of high-performance, centralized laboratory of Molecular Biology Research Foundation of the General Hospital of Valencia.
 
Centralized platform in several laboratories in the Molecular Biology Research Foundation of the Hospital General de Valencia.
Both physicians and technical staff of this platform has the experience and ability to manage and analyze large numbers of samples to ensure the services offered by it.
 
Molecular Biology Laboratory of the Hospital General de Valencia Foundation.
Foundation University Hospital of Valencia.
 
Services:
Multigenic-Affymetrix analysis:
- Expression.
- Genotyping.
 
Multigenic analysis, Illumina:
- Expression.
- Genotyping.
- Methylation.
 
Sequenase Platform:
 - Expression.
- Genotyping.
- Methylation.
 
Massive sequencing with the Illumina platform.
 
Platform Infrastructure:
DX2 Affymetrix microarray platform validated for clinical use by the FDA.
Real time 7900HT thermocycler plate 96, 384 and microfluidias cards for real Time-based microarrays.
 XL ABI3130 capillary sequencer with 16 capillaries.
Fluidigm thermocycler in nanofluids.
Luminex DX100.
Zeptosens platform for protein microarrays.
Leica Microdisector DFM6000.
Leica Cryostat CM19000pàra partor RNA extraction of samples included in OCT.
Microtomes.
ABI3100 nucleic acid extractor.
Robot cleaner exhaust and nucleic acids Quiacube of Quiagen.
EVO robotic sample preparation.
Tissue homogenizers dyed Lyser of QuiaGen.
Bioanalizadors (2) from Agilent.
Nanodrop spectrophotometer.
White Board room free of particles for molecular biology studies.

- The performance of services by the PTS is subject to the rates set for each process, although they may be amended in accordance with the commitments of collaboration that may arise between the applicant researcher and services specific PTS.
 
- Management of PTS services are made ¿¿through the coordinator of the RVB who according to the nature of requests contact with the coordinators of the PTS.
 
- Each PTS coordinator will conduct an evaluation of services that have been requested and an estimate of time needed for their implementation.
 
- After evaluating the proposal, a budget will be issued by each biobank and / or PTS laboratory investigator with an estimate of the execution time of them.
 
- Do not take out any service without the acceptance of the budget by the investigator nor the firm's commitment to performance by the biobank / laboratory performing the services regardless of the type of agreement that the parties can reach.

- The coordinator of the RVB will monitor the implementation process of the services to ensure compliance with the deadlines established and communicated to the researcher responsible for any incident arising during the implementation process.